- Kyle, K.E.†; Puckett, S.P.†; Caraballo-Rodríguez, A.M.; Rivera-Chávez, J.; Samples, R.M.; Earp, C.E.; Raja, H.A.; Pearce, C.J.; Earnst, M.; van der Hooft, J.J.J.; Adams, M.E.; Oberlies, N.H.; Dorrestein, P.C.; Klassen, J.L.*; Balunas, M.J.* Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma-derived metabolite cues. Preprint, https://doi.org/10.1101/2022.11.12.516288 †These authors contributed equally.
- Pasternak, A.R.O.; Balunas, M.J.; Zechel, D.L. Discovery of 3'-O-beta-glucosyltubercidin and the nucleoside specific glycosyltransferase AvpGT through genome mining. ACS Chem. Biol., 2022, in press. Link
- Samples, R.M.; Puckett, S.P.; Balunas, M.J.* MPACT: an advanced informatics tool for metabolomics and data visualization of specialized metabolites from complex microbial samples. Preprint, https://doi.org/10.26434/chemrxiv-2022-r0xbx
- Jin, Y.; Schladetsch, M.A.; Huang, X.; Balunas, M.J.; Wiemer, A.J. Stepping forward in antibody-drug conjugate development. Pharmacol. Ther., 2022, 229, 107917. Link
- Tan, K.C.; Pham, T.X.; Lee, Y.; Lee, J.-Y.; Balunas, M.J.* Identification of apocarotenoids as chemical markers of in vitro anti-inflammatory activity for spirulina supplements. J. Ag. Food Chem., 2021, 69, 12674-12685. Link
- Clark, K.E.; Capper, A.; Liu, W.-T.; Fenner, A.M.; Almanza, A.; Della Togna, G.; Herrera, L.; Johns, T.; Dorrestein, P.C.; Paul, V.P.; Capson, T.L.; Balunas, M.J.* Sequestration and cyanobacterial diet preferences in the opisthobranch molluscs Dolabrifera nicaraguana and Stylocheilus rickettsi. Front. Mar. Sci., 2021, 8, 766282. Link
- Caraballo-Rodríguez, A.M.; Puckett, S.P.; Kyle, K.E.; Petras, D.; da Silva, R.; Nothias, L.-F.; Ernst, M.; van der Hooft, J.J.J.; Tripathi, A.; Wang, M.; Balunas, M.J.; Klassen, J.L.*; Dorrestein, P.C.* Chemical gradients of plant substrates in an Atta texana fungus garden. mSystems, 2021, 6, e00601-21. Link
- Balunas, M.J.; Cragg, G.M.; Gibbons, S.; Mata, R. Professor A. Douglas Kinghorn. A lifetime career dedicated to outstanding service to natural product sciences. J. Nat. Prod., 2021, 84, 549-552. (editorial) Link
- Hagan, A.K.; Lesniak, N.A.; Balunas, M.J.; Bishop, L.; Close, W.L.; Doherty, M.D.; Elmore, A.G.; Flynn, K.L.; Hannigan, G.D.; Koumpouras, C.; Jenior, M.L.; Kozik, A.J.; McBride, K.; Rifkin, S.B.; Stough, J.M.A.; Sovacool, K.L.; Sze, M.A.; Tomkovich, S.; Topcuoglu, B.D.; Schloss, P.D.* Ten simple rules to increase computational skills among biologists with code clubs. PLoS Comput. Biol., 2020, 16, e1008119. Link
- Suria, A.M.†; Tan, K.C.†; Kerwin, A.H.; Gitzel, L.; Abini-Agbomson, L.; Bertenshaw, J.M.; Sewell, J.; Nyholm, S.V.*, Balunas, M.J.* Hawaiian bobtail squid symbionts inhibit marine bacteria via specialized metabolite production, including new bromoalterochromides, BAC-D/D'. mSphere, 2020, 5, e00166-20. †These authors contributed equally. Link
- Samples, R.M.; Balunas, M.J.* Bridging the gap: Plant-endophyte interactions as a roadmap to understanding small molecule communication in marine microbiomes. ChemBioChem, 2020, 21, 2708-2721. Link
- Maloney, K.N.*; Botts, R.T.; Davis, T.S.; Okada, B.K.; Maloney, E.M.; Leber, C.A.; Alvarado, O.; Brayton, C.; Caraballo, M.; Chari, J.V.; Chicoine, B.; Crompton, J.C.; Davis, S.R.; Gromek, S.M.; Kurnianda, V.; Quach, K.; Samples, R.M.; Shieh, V.; Sultana, C.M.; Tanaka, J.; Dorrestein, P.C.; Balunas, M.J.; McFadden, C.S.* Cryptic species account for the seemingly idiosyncratic secondary metabolism of Sarcophyton glaucum specimens collected in Palau. J. Nat. Prod., 2020, 83, 693-705. Link
- Puckett, S.P.†; Samples, R.M.†; Schloss, P.D.; Balunas, M.J.* Metabolomics and the microbiome: Characterizing molecular diversity in complex microbial communities. In Comprehensive Natural Products III: Chemistry and Biology; Liu, H.-W. and Begley, T.P., Eds.; Elsevier: London, 2020; pp 502-518. †These authors contributed equally. Link
- Wang, M.; Jarmusch, A.K.; Vargas, F.; Aksenov, A.A.; Gauglitz, J.M.; Weldon, K.; Petras, D.; da Silva, R.; Quinn, R.; Melnik, A.V.; van der Hooft, J.J.J.; Caraballo Rodríguez, A.M.; Nothias, L.F.; Aceves, C.M.; Panitchpakdi, M.; Brown, E.; Di Ottavio, F.; Sikora, N.; Elijah, E.O.; Labarta-Bajo, L.; Gentry, E.C.; Shalapour, S.; Kyle, K.E.; Puckett, S.P.; Watrous, J.D.; Carpenter, C.S.; Bouslimani, A.; Ernst, M.; Swafford, A.D.; Zúñiga, E.I.; Balunas, M.J.; Klassen, J.L.; Loomba, R.; Knight, R.; Bandeira, N.; Dorrestein, P.C.* MASST: A web-based basic mass spectrometry search tool for molecules to search public data. Nat. Biotechnol., 2020, 38, 23-26. Link
- Kerwin, A.H.†; Gromek, S.M.†; Suria, A.M.; Samples, R.M.; Deoss, D.J.; O’Donnell, K.; Frasca, S., Jr.; Sutton, D.A.; Wiederhold, N.P.; Balunas, M.J.*; Nyholm, S.V.* Shielding the next generation: symbiotic bacteria from a reproductive organ protect bobtail squid eggs from fungal fouling. mBio, 2019, 10, e02376-19. †These authors contributed equally. Link
- van Santen, J.A.; Jacob, G.; Singh, A.L.; Aniebok, V.; Balunas, M.J.; Bunsko, D.; Carnevale Neto, F.; Castaño-Espriu, L.; Chang, C.; Clark, T.N.; Clearly Little, J.L.; Delgadillo, D.A.; Dorrestein, P.C.; Duncan, K.R.; Egan, J.M.; Galey, M.M.; Haeckl, F.P.J.; Hua, A.; Hughes, A.H.; Iskakova, D.; Khadilkar, A.; Lee, J.-H.; Lee, S.; LeGrow, N.; Liu, D.Y.; Macho, J.M.; McCaughey, C.S.; Medema, M.H.; Neupane, R.P.; O'Donnell, T.J.; Paula, J.S.; Sanchez, L.M.; Shaikh, A.F.; Soldatou, S.; Terlouw, B.R.; Tran, T.A.; Valentine, M.; van der Hooft, J.J.J.; Vo, D.A.; Wang, M.; Wilson, D.; Zink, K.E.; Linington, R.G.* The Natural Products Atlas: An open access knowledge base for microbial natural products discovery. ACS Cent. Sci., 2019, 5, 1824-1833. Link
- Tayler, N.M.; Boya, C.A.; Herrera, L.; Moy, J.; Ng, M.; Pineda, L.; Almanza, A.; Rosero, S.; Coronado, L.M.; Correa, R.; Santamaría, R.; Caballero, Z.; Duran-Archibold, A.A.; Tidgewell, K.J.; Balunas, M.J.; Gerwick, W.H.; Spadafora, A.; Gutiérrez, M.; Spadafora, C. Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién. PLoS One, 2019, 14, e0214193. Link
- Trexler, S.; Nguyen, E.; Gromek, S.M.; Balunas, M.J.; Baker, B.L. Electrocardiographic effects of hawthorn (Crataegus oxycantha) in healthy volunteers: A randomized controlled trial. Phytother. Res., 2018, 32, 1642-1646. Link
- da Silva, R.R.; Wang, M.; Nothias, L.-F.; van der Hooft, J.J.J.; Caraballo-Rodríguez, A.M.; Fox, E.; Balunas, M.J.; Klassen, J.L.; Lopes, N.P.; Dorrestein, P.C. Propagating annotations of molecular networks using in silico fragmentation. PLoS Comput. Biol., 2018, 14, e1006089. Link
- Sung, A.A.†; Gromek,S.M.†; Balunas, M.J.* Upregulation and identification of antibiotic activity of a marine-derived Streptomyces sp. via co-cultures with human pathogens. Mar. Drugs, 2017, 15, 250. †These authors contributed equally. Link
- Juliano, S.A.; Pierce, S.; deMayo, J.A.; Balunas, M.J.; Angeles-Boza, A.M. Exploration of the innate immune system of Styela clava: Zn2+ binding enhances the antimicrobial activity of the tunicate peptide clavanin A. Biochem., 2017, 56, 1403-1414. Link
- deMayo, J.A.; Maas, K.R.; Klassen, J.L.; Balunas, M.J.* Draft genome sequence of Streptomyces sp. AVP053U2 isolated from Styela clava, a tunicate collected in Long Island Sound. Genome Announc., 2016, 4, e00874-16. Link
- Gromek, S.M.; deMayo, J.A.; Maxwell, A.T.; West, A.M.; Pavlik, C.M.; Zhao, Z.; Li, J.; Wiemer, A.J.; Zweifach, A.; Balunas, M.J.* Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity. Bioorg. Med. Chem., 2016, 24, 5183-5196. Link
- Gromek, S.M.; Sung, A.A.; Klassen, J.L.; Balunas, M.J.* Draft genome sequence of Streptomyces sp. strain PTY087I2 isolated from Styela canopus, a Panamanian tunicate. Genome Announc., 2016, 4, e00856-16. Link
- Gromek, S.M.†; Suria, A.†; Fullmer, M.S.; Garcia, J.L.; Gogarten, J.P.; Nyholm, S.V.*; Balunas, M.J.* Leisingera sp. JC1, a bacterial isolate from Hawaiian bobtail squid eggs, produces indigoidine and differentially inhibits vibrios. Front. Microbiol., 2016, 7, 1342. †These authors contributed equally. Link
- Zhao, Z.; deMayo, J.A.; West, A.M.; Balunas, M.J.*; Zweifach, A.* Development of an enhanced phenotypic screen of cytotoxic T lymphocyte lytic granule exocytosis suitable for use with synthetic compound and natural product collections. J. Biomol. Screen, 2016, 21, 556-566. Link
- Tao, G.; Balunas, M.J.* Current therapeutic role and medicinal potential of Scutellaria barbata in Traditional Chinese Medicine and Western research. J. Ethnopharmacol., 2016, 182, 170-180. Link
- Doucette, J.; Zhao, Z.; Geyer, R.J.; Barra, M.M.; Balunas, M.J.; Zweifach, A. Flow cytometry enables multiplexed measurements of genetically-encoded intramolecular FRET sensors suitable for screening. J. Biomol. Screen, 2016, 21, 535-547. Link
- Fenner, A.M.; Engene, N.; Spadafora, C.; Gerwick, W.H.; Balunas, M.J.* Medusamide: A Panamanian cyanobacterial depsipeptide with multiple β-amino acids. Org. Lett. 2016, 18, 352-355. Link
- Ku, C.-S.; Kim, B.; Pham, T.X.; Yang, Y.; Wegner, C.J.; Park, Y.-K.; Balunas, M.J.; Lee, J.-Y. Blue-green algae inhibit the development of atherosclerotic lesions in apolipoprotein E knockout mice. J. Med. Food 2015, 18, 1-8. Link
- Shao, C.-L.; Linington, R.G.; Balunas, M.J.; Centeno, A.; Boudreau, P.; Zhang, C.; Engene, N.; Spadafora, C.; Mutka, T.S.; Kyle, D.E.; Gerwick, L.; Wang, C.-Y.; Gerwick, W.H. Bastimolide A, a potent antimalarial polyhydroxy macrolide from the marine cyanobacterium Okeania hirsuta. J. Org. Chem. 2015, 80, 7849-7855. Link
- Gromek, S.M.; West, A.W.; Balunas, M.J.* Off the beathen path: Natural products from extreme environments. In Marine Biomedicine: From Beach to Bedside; Baker, B.J., Ed.; CRC Press: Boca Raton, FL, 2015; Chapter 12, pp 341-378.
- Gromek, S.M.; Balunas, M.J.* Natural products as exquisitely potent cytotoxic payloads for antibody-drug conjugrates. Curr. Top. Med. Chem. 2014, 14, 2822-2834. Link
- Carneiro, V.M.T.; Avila, C.M.; Balunas, M.J.; Gerwick, W.H.; Pilli, R.A. Coibacins A and B: Total synthesis and stereochemical revision. J. Org. Chem. 2014, 79, 630-642. Link
- Pavlik, C.M.; Wong, C.Y.B.; Ononye, S.; Lopez, D.D.; Engene, N.; McPhail, K.L.; Gerwick, W.H.; Balunas, M.J.* Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. J. Nat. Prod. 2013, 76, 2026-2033. Link
- Gerwick, L.; Boudreau, P.; Choi, H.; Mascuch, S.; Villa, F.A.; Balunas, M.J.; Malloy, K.; Teasdale, M.E.; Rowley, D.C.; Gerwick, W.H. Interkingdom signaling by structurally related cyanobacterial and algal secondary metabolites. Phytochem. Rev. 2013, 12, 459-465. Link
- Balunas, M.J.* Attempting to solve the disconnect between humans and nature with plant-based drugs. Ecol. 2013, 94, 262-263. Link
- Balunas, M.J.; Grosso, M.F.; Villa, F.A.; Engene, N.; McPhail, K.L.; Tidgewell, K.; Pineda, L.M.; Gerwick, L.; Spadafora, C.; Kyle, D.E.; Gerwick, W.H. Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins. Org. Lett. 2012, 14, 3878-3881. Link
- Balunas, M.J.*; Kinghorn, A.D. Natural product compounds with aromatase inhibitory activity: An update. Planta Med. 2010, 76, 1087-1093. Link
- Balunas, M.J.; Linington, R.G.; Tidgewell, K.; Fenner, A.M.; Ureña, L.D.; Kyle, D.E.; Gerwick, W.H. Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity. J. Nat. Prod. 2010, 73, 60-66. Link
- Deng, Y.; Balunas, M.J.; Kim, J.-A.; Lantvit, D.D.; Chin, Y.-W.; Chai, H..; Sugiarso, S.; Kardono, L.B.S.; Fong, H.H.S.; Pezzuto, J.M.; Swanson, S.M.; Carcache de Blanco, E.J.; Kinghorn, A.D. Bioactive 5,6-dihydro-α-pyrone derivatives from Hyptis brevipes. J. Nat. Prod. 2009, 72, 1165-1169. Link
- Balunas, M.J.; Su, B.; Riswan, S.; Fong, H.H.S.; Brueggemeier, R.W.; Pezzuto, J.M.; Kinghorn, A.D. Isolation and characterization of aromatase inhibitors from Brassaiopsis glomerulata (Blume) Regel. Phytochemistry Lett. 2009, 2, 29-33. Link
- Balunas, M.J.; Su, B.; Brueggemeier, R.W.; Kinghorn, A.D. Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity. J. Nat. Prod. 2008, 71, 1161-1166. Link
- Balunas, M.J.; Su, B.; Brueggemeier, R.W.; Kinghorn, A.D. Natural products as aromatase inhibitors. Anticancer Agents Med. Chem. 2008, 8, 646-682. Link
- Chin, Y.-W.; Balunas, M.J.; Chai, H.B.; Kinghorn, A.D. Drug Discovery from Natural Sources. In Drug Addiction. From Basic Research to Therapy; Rapaka, R.S., Sadée, W., Eds.; Springer/AAPS Press, New York, 2008; pp 17-39. (content appeared previously in AAPS J.)
- Balunas, M.J.; Jones, W.P.; Chin, Y.-W.; Mi, Q.; Farnsworth, N.R.; Soejarto, D.D.; Cordell, G.A.; Swanson, S.M.; Pezzuto, J.M.; Chai, H.-B.; Kinghorn, A.D. Relationships between inhibitory activity against a cancer cell line panel, profiles of plants collected, and compound classes isolated in an anticancer drug discovery project. Chem. Biodivers. 2006, 3, 897-915. Link
- Chin, Y.-W.; Balunas, M.J.; Chai, H.B.; Kinghorn, A.D. Drug discovery from natural sources. AAPS J. 2006, 8, E239-E253. Link
- Balunas, M.J.; Su, B.; Landini, S.; Brueggemeier, R.W.; Kinghorn, A.D. Interference by naturally occurring fatty acids in a non-cellular, enzyme-based aromatase bioassay. J. Nat. Prod. 2006, 69, 700-703. Link
- Balunas, M.J.; Kinghorn, A.D. Drug discovery from medicinal plants. Life Sci. 2005, 78, 431-441. Link
- Balunas, M.J.; Kimmerer, R.W. 2002. The restoration potential of goldthread, an Iroquois medicinal plant. Ecol. Restor. 2002, 20, 59-60. Link